< PrevNext > 43. Merck & Co. Kenilworth, N.J. Share 2016 U.S.-Booked Air Volume: $94 millionPrimary Card Supplier: American ExpressConsolidated U.S. TMC: Amex GBTPharmaceutical giant Merck & Co.'s U.S.-booked air spending increased in 2016, according to a BTN estimate. Worldwide sales for Merck & Co., known outside the U.S. and Canada as MSD, were $39.8 billion, an increase of 1 percent compared with 2015. For 2015, the most recent year for which data was available, Merck & Co. generated 283,300 metric tons of carbon dioxide equivalent, including air, rail, hotel, rental car use and reimbursable employee driving mileage. That was an increase of 55 percent from 2014. To limit emissions, Merck & Co. encourages employees to use remote conferencing, and its online booking tool includes rail options to promote lower-emission travel. American Express Global Business Travel services Merck & Co. travel in the Americas and Europe, while BCD Travel services the Asia/Pacific region. Merck & Co. works with Amex GBT for strategic meetings management services. Merck & Co. had about 68,000 employees at the end of 2016, about the same as a year prior.