< PrevNext > 80. Stryker Kalamazoo, Mich. Share 2016 U.S.-Booked Air Volume: $54 millionMedical device and equipment manufacturer Stryker's U.S.-booked air volume increased almost 17 percent in 2016, according to a BTN estimate. Revenue totaled $11.3 billion, a 14 percent increase from 2015. The company employed approximately 33,000 employees in 2016, up from 26,000 in 2015. In 2015, it merged its European and U.S. businesses and in 2016 extended its transatlantic operating model to Canada. Last year, Stryker invested $4 billion in acquisitions: Its medical division acquired Sage Products and Physio-Control International, and the company completed other small acquisitions across its three operating segments.